Setting Up Ledger Live and Your Ledger Device. Connect Your Ledger Live App Device: Use the USB cable provided with your Ledger device (Nano S, Nano X, etc.) to connect it to your computer. Initialize Your Ledger Device: If you haven't already initialized your Ledger device, follow the on-screen instructions on the device to set it up. This typically Use the 'My Ledger' section in the Ledger Live app to install or uninstall apps on your Ledger device. How apps work Your Ledger device securely stores your private keys giving access to your crypto assets. Ledger Live Apps are blockchain apps you can access directly through the ‘Discover’ feature. These third-party applications let you extend the features of your Ledger Live App device and your web3 experience, giving you more ways to use it. So, how does it all work? Put simply, Ledger Live has an easy-to-use interface that provides you with easy access to apps and